(Extract from article by David Prentice)
Umbilical cord blood stem cells have become an extremely valuable alternative to bone marrow adult stem cell transplants, ever since cord blood stem cells were first used for patients over 25 years ago. The first umbilical cord blood stem cell transplant was performed in October 1988, for a 5-year-old child with Fanconi anemia, a serious condition where the bone marrow fails to make blood cells. That patient is currently alive and healthy, 25 years after the cord blood stem cell transplant.
Since that time, over 30,000 cord blood stem cell transplants have been done around the world, and transplants have increased for various blood and bone marrow diseases and leukemias, as well as for genetic enzymatic diseases in children. Cord blood stem cell transplants have also become more common for adults with leukemia. Cord blood transplants have been especially helpful for racial and ethnic minorities.
Bone marrow adult stem cell transplants require an exact match between donor and recipient, and it can sometimes be difficult to find a donor match for a patient, especially for minorities. But umbilical cord blood stem cells can be used with some mismatch and still provide successful treatments.**
The Wall Street Journal recently noted the increased interest in umbilical cord blood by scientists and doctors seeking stem cell cures. Besides current treatments, cord blood stem cells are now being studied for their potential to treat many more diseases, including Type 1 diabetes and rheumatoid arthritis, as well as congenital heart disease and cerebral palsy. The story quotes Dr. William Shearer, professor of pediatrics and immunology at Baylor College of Medicine:
“It’s a disposable item that Mother Nature provides us with… It’s a renewable source. It’s free and why not use it?”
Since the first umbilical cord blood stem cell transplant over 25 years ago, over 600,000 cord blood units have been stored away around the globe for future lifesaving transplants. Just two examples of public programs to collect and store umbilical cord blood stem cells are the National Marrow Donor Program (motto: “You could cure someone’s blood cancer by giving birth”) and the National Cord Blood Program, and additionally there are commercial cord blood storage companies, involved in collection, storage, and research. The data so far show that cord blood stem cells can be stored frozen for over 20 years without loss of potency.
And it’s not controversial. As a recent news story in the Washington Times showed, many more states are turning to ethical, successful adult stem cells, providing real hope and real treatments for thousands of people. One such state, Kansas, last year initiated a unique Midwest Stem Cell Therapy Center that will treat patients, do research on new therapies, educate the public and professionals on the advantages of adult stem cells such as those from cord blood and the solid umbilical cord, and train physicians to deliver those treatments. Paul Wagle was appointed by Governor Brownback to represent the patient community on the new Advisory Board for the Kansas Center. Paul received an umbilical cord blood stem cell transplant for his leukemia in 2005. Partly as a result of the successful treatment, Paul developed an interest in science and earned a triple major from Benedictine College in Kansas in 2013, and is now in seminary. The Kansas Center has already treated its first patient and held its inaugural scientific conference.
Here are just a few other examples of the double lifesaving from a born baby and the saved cord blood.
Mary Lou Rusco also received umbilical cord blood stem cells for her leukemia. She received the treatment from doctors at the Kansas University Medical Center, and is now free from leukemia.
Joe Davis, Jr. was diagnosed with sickle cell anemia, at only a few months old. His parents were told that he wouldn’t survive to be a teenager, and they couldn’t find a bone marrow match for him. But along came younger brother Isaac, whose umbilical cord blood stem cells saved Joe Junior’s life.
Chloe Levine received an innovative cord blood stem cell transplant at Duke University to treat her cerebral palsy. She’s now a happy healthy little girl.
**As accurate and meaningful as this excerpt is, it is too conservative in 2014. Yes, in 2010 it may have been considered correct, but today, umbilical cord stem cells (UCSC) are rapidly becoming the adult stem cells of choice at our world- leading 14 clinics. There are two reasons for this: (1) Matching UCSC, as they must for bone marrow transplants, is a waste of time. The ultra-modern, super-clean cutting-edge labs which produce them deliver a product without DNA markers. This means that the receiving patient's immune system cannot reject them as "strange DNA." (2) Even more exciting, is that the stem cell leaders are choosing the rare "mesenchymal" stem cells rather than the commonplace stem cells found in bone marrow, adipose, or umbilical cords because they can become virtually any kind of tissue cell the patient may need. Since the mesenchymal numbers are something like 1/1000 of the common cells, they must be cultured and grown over time---normally 2-3 months with bone marrow and adipose, making the patient wait or make two trips to the clinic. But the new M-UCSC are prepared and delivered to the treating doctors before the patient even arrives, meaning he now gets mesenchymals without any delay!---Repair Stem Cells Institute
Michele Bachmann is the owner of Grapes 2 Glass Wine Boutique, 10351 Washington Ave., Suite 200, in Sturtevant. Bachmann has overcome a very aggressive form of cancer, thanks in large part to a stem cell transplant. She initially was given 18 months to live, or until she’d need another transplant. She’s had neither and is still in remission six years later. In the past, the average survival for her type of cancer has been two to three years.
RACINE COUNTY — After more than four decades, Michele Bachmann knew her body well enough to know there was something definitely wrong.
Yet it would be almost a year of frustration, aggravation and suffering before her feelings would receive validation — ultimately landing her in a grueling fight to save her life.
“I kept saying I was sick. People thought I was crazy,” she said. “I just kind of felt off, tired. Things just weren’t right.”
Bachmann, 50, who lives in Racine, said she contacted the doctor, who ran some blood tests.
“He said everything was fine. He said I just need to lose some weight and sit at my desk properly,” Bachmann said, giving her head a slight shake.
It wasn’t until later that she learned those tests results showed something more: Her white blood cell count was high.
“He said ‘oh no, you need to exercise, lose weight, take vitamins,’ ” she said. “By the time I got diagnosed in August, my spleen was the size of a basketball and weighed 25 pounds.”
It was about 11 months from the time she first knew she was sick before Bachmann — who owns Grapes 2 Glass Wine Boutique, at 10351 Washington Ave., Suite 200, in Sturtevant — received the proper diagnosis. It just wasn’t the one anyone wanted to hear.
She was in so much pain one day that she couldn’t make it to work in North Chicago, Ill., where she was a wine consultant. Her doctor was on vacation, so she went into prompt care. They took some blood, and she went home to make lunch, she said. They called her to come back because she was so low on blood. She received a transfusion, requiring three or four units, she said.
While at the hospital with her husband, parents and a friend, a doctor walked into her room, Bachmann recalled as if he stepped through that door only yesterday.
“He said ‘we just got the test results. You have leukemia,’ ” she recounted. “Everyone was in hysterics. It was a relief to me. I knew I was sick.”
He performed her first bone marrow biopsy while she still was in Wheaton Franciscan-All Saints hospital, 3801 Spring St., she said.
“It was probably one of the most horrible things I’ve ever done,” Bachmann said. “I was holding onto the railing of the bed and I probably could have broken the railing.”
But the doctor there wasn’t familiar with the type of cancer she had, Bachmann said.
Bachmann, who has nine siblings, said she called her sister, who had just completed a three-month course of chemotherapy at Froedtert Hospital in Wauwautosa because of tumors along her spinal column.
Her sister’s doctor recommended a new doctor at Froedtert, Timothy Fenske, Bachmann said. Fenske, a medical oncologist at Froedtert & The Medical College of Wisconsin, said he started working at the hospital in July 2005, and met Bachmann the following month.
He said she had mantle cell lymphoma. It is a type of non-Hodgkin’s lymphoma, he said.
“She had a lot of disease in her system,” Fenske said.
So she had a choice — the first of multiple tough decisions.
“They said where you’re at, you’ve got about two weeks to live. They explained my cancer is mainly in older men,” Bachmann said. “They said it’s only 4 percent of the types of leukemias and lymphomas. (Fenske) said ‘we could make you comfortable, or we could have you try this clinical going on right now.’ ”
But the course of treatment would be very strong.
“I said ‘if I’m gonna die in two weeks, what does it matter?’ ” Bachmann said.
She began her first chemo treatment in August 2005, and it truly was brutal, she explained. She developed sores inside her mouth. She lost her hair. She repeatedly lost her lunch. She became so weak she barely could move, she recalled.
Fenske said because Bachmann was so strong and young, and had such an extensive family support network, he suggested she undergo this type of high-dose chemotherapy. The average age of patients with Bachmann’s type of lymphoma is 63, he said.
“I thought chemo was chemo,” said Michele’s husband, Steve Bachmann. “Apparently there are hundreds of types.”
Looking back, Michele Bachmann can laugh at one type of chemo. She said the warning that came with it basically stated if she was allergic to eating rats, she might have a problem with it.
“I said, ‘well, I’ve never eaten rats, so we should be OK,’ ” she laughed.
“She’s one of our favorites,” Fenske said of Bachmann, in part because of her sense of humor. “Some people are a real challenge to get through chemotherapy. She was a trouper through it. Some people are really high maintenance.”
Often during chemo, patients’ sense of taste will be affected.
“Her thing was pickles,” Fenske said with a laugh. “She’d have this huge jar of pickles (when she came for chemo). I don’t know how many she’d work through.”
He said he suggested this type of aggressive chemotherapy because he wanted to send Bachmann’s cancer into remission, then dose her with stem cells he would transplant into her.
Stem cells are found throughout the body, including in bone marrow. Stem cells are a very basic building-block type of cells. In stem cell transplants, a batch of healthy cells is inserted into the body.
Froedtert spokeswoman Nalissa Wienke said “stem cell transplants are often the last best hope for patients.”
To help Bachmann’s body rebuild, Fenske gave her another choice, Bachmann said. She could use her own stem cells, or receive a transplant from a donor — such as one of her siblings. She chose her own stem cells, receiving the transplant Feb. 15, 2006.
Fenske said there are pros and cons to using one’s own stem cells and to using a donor’s.
Using one’s own stem cells allows doctors to administer high-dose chemotherapy, which works better at treating this type of cancer, but can leave patients without functioning bone marrows, Fenske said.
Transplanting the patient’s own stem cells also allows patients to recover better from this more aggressive, high-dose chemotherapy, Fenske explained. And it carries less of a risk — just 1 percent to 2 percent — of infection or a serious complication, he added.
So in Bachmann’s case, “it’s her own immune system coming back,” Fenske said.
But when a donor’s stem cells are used, patients would have to take anti-rejection drugs. And, they have more risk of infection, Fenske explained, at 15 percent to 20 percent.
“Historically, (with) the type of lymphoma she had, the average person only lived two to three years after diagnosis. In recent years, the prognosis has increased dramatically,” Fenske said.
Now, 50 to 60 percent of patients who receive high-dose chemotherapy and their own stem cells still are in remission six years later, Fenske said — just as Bachmann is.
An 8- to 10-year period is considered a good length of remission, Fenske said. And if it returns, he said Bachmann still could have a stem cell transplant from a donor.
“I’m just extremely, extremely happy” to be cancer-free for the past six years, she said. “I feel good.”
During the first couple of years after chemo and the transplant, she said she was waiting for the cancer to come back, almost preparing for it.
“(Now) if I feel run down, I know I didn’t go to bed early enough. I don’t have that really crappy feeling anymore,” Bachmann said. “Now I’ve got two birthdays. One in April and one on Feb. 15 — that’s my new life.”
BODY DIES, STEM CELLS GO DORMANT AND SURVIVE FOR 2+ WEEKS
"Scientists around the world are shocked, but they shouldn't be," says Don Margolis
Under the direction of Fabrice Chrétien, in collaboration with Shahragim Tajbakhsh, researchers from the Institut Pasteur, the Université de Versailles Saint-Quentin-en-Yvelines, the Paris Public Hospital Network (AP-HP), and the CNRS have shown for the first time in humans and mice, the capacity of stem cells to adopt a dormant state when their environment becomes hostile, including several days after death. This ability to significantly reduce metabolic activity enables them to preserve their potential for cellular division, even after extended periods post mortem. After isolation, they can then be used to repair damaged organs or tissues. This discovery could lead to new therapeutic avenues for treating numerous diseases. The study is being published in the journal Nature communications.
Remarkably, skeletal muscle stem cells can survive for seventeen days in humans and sixteen days in mice, post mortem well beyond the 1-2 days currently thought. This discovery was made by researchers from the Institut Pasteur, the Université de Versailles Saint-Quentin-en-Yvelines, the Paris Public Hospital Network (AP-HP), and the CNRS under the direction of Professor Fabrice Chrétien*, in collaboration with a team led by Professor Shahragim Tajbakhsh**. The scientists were also able to show that these stem cells, once back in culture, retained their capacity to differentiate into perfectly functioning muscle cells.
In light of this astonishing result, scientists then sought to characterize these cells to understand how they survive in such adverse conditions. They observed that these cells enter a deeper state of quiescence, drastically lowering their metabolism. This so-called "dormant" state is a result of cellular organization that is stripped to the bare minimum: fewer mitochondria (cellular power plants using oxygen to produce energy in cells) and diminished stores of energy.
“We can compare this to pathological conditions where cells are severely deficient in resources, before regaining a normal cell cycle for regenerating damaged tissues and organs, explains Fabrice Chrétien. When muscle is in the acute phase of a lesion, the distribution of oxygen is highly disrupted. We have even observed that muscle stem cells in anoxia (totally deprived of oxygen) at 4°C have a better survival rate than those regularly exposed to ambient levels of oxygen.”
The team of Fabrice Chrétien then wondered if these results were consistent with other cell types. Tests were then done on stem cells taken from bone marrow where blood cells are produced. These cells remained viable for four days in post mortem mice models, and more importantly, they retained their capacity to reconstitute tissue after a bone marrow transplant.
This discovery could form the basis of a new source, and more importantly new methods of conservation, for stem cells used to treat a number of pathologies. This is the case for leukemia, for example, which requires a bone marrow transplant to restore a patient's blood and immune cells destroyed by chemotherapy and radiation. By harvesting stem cells from the bone marrow of consenting donors post mortem, doctors could address to a certain extent the shortage of tissues and cells. Although highly promising, this approach in the realm of cellular therapy still requires more testing and validation before it can be used in clinical applications. Nevertheless, it paves the way to investigate the viability of stem cells from all tissues and organs post mortem.
From Don: "Scientists around the world are shocked, but they shouldn't be, because Repair Stem Cells are created to divide, grow and cure, no matter what the obstacles. There are many many obstacles which can slow or stop that repair, but we are constantly finding ways around them. Now we know it will be possible in the future to collect stem cells (which are smart enough to go dormant) from a recently deceased body, test them, and use them to help another patient."
TEXAS GOVERNOR FIGHTING BIG MEDICINE POWERS---STRUGGLING TO GET THE TRUTH ABOUT STEM CELLS TO A DECEIVED PUBLIC
Rick Perry knows as well as Don Margolis that Repair (Adult) Stem Cells (ASC) are the only stem cells capable of helping patients today. But he is learning in 2011 what Don learned (and wrote about) in 2008-2010: Big Medicine (which owns the US government and runs the FDA) will never allow patients to be cured or even helped. In Amerika, profits are all that matter in medicine and patients come in last. That is why we spend 18% of our GNP making the rich profiteers richer, while the second most expensive country spends only 12%. That is why prescriptions cost 150%-250% in the USA of what they cost in Canada and Europe. That is why a $5000 hospital procedure in Europe costs $20,000 in the USA.
In order to keep the scam going, they control every major newspaper, magazine, TV network, and major website in North America. Read this article from an Austin TX newspaper and see all the lies and misinformation;
AUSTIN, Texas (AP) — The experimental (The liars always say "experimental," knowing full well that over 25,000 people around the world have been successfully treated with ASC
) stem cell procedure that Texas Gov. Rick Perry underwent this summer could be restricted or even blocked under new rules being considered Friday by the state's Medical Board. (Because doctors make bundles in commissions and referral fees and outrageously high rates under this crooked system, they will vote the way Big Medicine pays them to vote.
Some top scientists are questioning the safety and wisdom of the procedure, and doctors say it may run up against federal rules. It also carries potential health threats, ranging from blood clots to increased cancer risk. (When YOUR lying doctor mentions these non-existent risks, ask him to name one patient who got blood clot or cancer from his own stem cells. American medicine kills a human being every minute due to incompetence, sloppiness, wrong drug dosages, misdiagnosis, etc. etc. Hospitals alone murder 15,000 a month---that's 1000 every two days, but your "top scientists" ignore their serial killing and con you about the safety of ultra safe stem cells.
The Republican presidential candidate had stem cells taken from fat in his own body, which were then grown in a lab. They were injected into his back and his bloodstream during an operation in July to fuse part of his spine.
Adult stem cells have long been used to treat leukemia, lymphoma and other cancers. (The usual lie of every bribed con man. Never mention the thousands of heart, lung, and diabetes patients being helped today---YOU ARE NOT ALLOWED TO KNOW THIS IN NORTH AMERICA!
) While the cells are being studied to treat other ailments, from heart disease to diabetes, experts say it's too soon to know if the approaches are safe or effective. (25,000 patients is not enough, but a few dozen in a corrupt clinical trial gets a drug approved because they hide the number of deaths the drug causes---or have you forgotten that a certain VIOXX killed 50,000 while Merck laughed all the way to the bank?
) The Food and Drug Administration hasn't approved using adult stem cells to help people heal from surgery — but experimentation is common.
Perry opposes greater oversight in Texas, and he sent a letter to the board urging members to recognize the "revolutionary potential" of adult stem cell research and therapies.
"Texas is a leader in innovation in many fields," Perry wrote after his surgery. "It is critical that we continue to foster an environment that encourages technological advancement in the health care arena."
IT IS ALMOST IMPOSSIBLE TO OVERCOME THE LIES BECAUSE ALL MAJOR MEDIA IN THE USA IS CONTROLLED 100% BY KORPORATE LIARS AND DECIEVERS. THE EXACT ARTICLE ABOVE, LIES AND ALL, WAS REPEATED IN VIRTUALLY EVERY MAJOR NEWSPAPER IN NORTH AMERICA AT THE INSISTENCE OF BIG PHARMA'S DECEPTION MACHINE; INCLUDING THE WASHINGTON POST, THE LA TIMES AND MOST BUSINESS MAGAZINES SUCH AS BUSINESS WEEK. PHARMA GETS A BRIBED CROOK TO WRITE AN ARTICLE AND THEN INSTRUCTS THEIR CONTROLLED PRESS TO SPREAD THE DECEPTION EVERYWHERE.
A survey of recent headlines about medical treatment received by Governor and potential presidential-hopeful Rick Perry of Texas could easily lead one to believe that he is a Texas-sized hypocrite when it comes to his opposition to human embryonic stem cell research. Once again, the mainstream media has things seriously wrong.
A Google search turns up articles with misleading titles, such as: “Stem Cell Critic Receives Stem Cell Therapy,” “Rick Perry has Stem Cell Procedure, Then Works to Bring it to Texas,” “Gov. Rick Perry Underwent Stem Cell therapy,” and “Report: Rick Perry Had Experimental Stem Cell Therapy.”
While there are a few exceptions, most of articles that address Gov. Perry’s treatment include titles that could easily lead one to believe that he accepted a treatment for his own medical condition that he has historically opposed for the treatment of others.
Of course, if you have the patience to read most of the articles carefully, you will see that the authors are forced to acknowledge that Gov. Perry’s treatment did not use stem cells taken from destroyed human embryos, and thus, he is not a “hypocrite” for opposing treatments that are based upon the use of such stem cells. In fact, it is the right position to take: opposing unethical research, while supporting ethical alternatives. Human embryonic stem cell research is morally wrong because it is rooted in the destruction of a human being; but other kinds of stem cell research, not involving the taking of a human being’s life, are not immoral.
Still, suspicious and judgmental reporting regarding Gov. Perry’s treatment
—and adult stem cell treatments in general—is typical of the mainstream media, seemingly bent upon advancing embryo-destructive stem cell research while downplaying the dramatic successes achieved through adult stem cell research. The media often seem blind to the simple (but clear) ethical differences.
Perhaps the most baffling and disingenuous aspect of the articles, however, is their (mis)characterization of adult stem cell research. For example, one article states that “the use of adult stem cells has not been proven to be effective.” Another quotes unnamed “researchers” who say that “they’ve seen nothing more definitive than the so-called ‘placebo effect’” from adult stem cell research.
In reality, treatments developed from adult stem cells are being used every day to treat once incurable diseases and serious injuries. Scientists have been able to help patients suffering from over 70 different diseases and injuries—including brain cancer, leukemia, lymphoma, Crohn’s disease, lupus, heart damage, Parkinson’s disease, Sickle cell anemia, and end-stage bladder disease—using adult stem cells. It is deeply disappointing that the media continues to treat these life-affirming advances as insignificant, while chasing what may well be a pipe dream that life-destroying embryonic stem cell research will one day yield dramatic results.